Our Partners:

img
img

 

A highly ranked scientific journal Nucleic Acids Research (NAR) has published our overview of the GTRD database.

The current version of the Gene Transcription Regulation Database (http://gtrd.biouml.org) contains information about: 

(1) transcription factor binding sites (TFBSs) and transcription coactivators identified by ChIP-seq experiments for Homo sapiens, Mus musculus, Rattus norvegicus, Danio rerio, Caenorhabditis elegans, Drosophila melanogaster, Saccharomyces cerevisiae, Schizosaccharomyces pombe and Arabidopsis thaliana;

(2) regions of open chromatin and TFBSs (DNase footprints) identified by DNase-seq; 

(3) unmappable regions where TFBSs cannot be identified due to repeats; 

(4) potential TFBSs for both human and mouse using position weight matrices from the HOCOMOCO database.

Web interface to access GTRD was developed using the BioUML platform. It provides browsing and displaying information, advanced search possibilities and an integrated genome browser.

The full text of this publication is available at https://academic.oup.com/nar/article/47/D1/D100/5184717